Identification of Mycobacterium tuberculosis DNA in a pre-Columbian Peruvian mummy.

  title={Identification of Mycobacterium tuberculosis DNA in a pre-Columbian Peruvian mummy.},
  author={W. Salo and A. Aufderheide and J. Buikstra and T. A. Holcomb},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={91 6},
The existence of tuberculosis in the pre-Columbian Americas is controversial because the morphology of the lesion is not specific, the organism is culturally nonviable in ancient tissues, and nonpathogenic soil mycobacteria can contaminate buried bodies. We report the recovery of DNA unique to Mycobacterium tuberculosis from a lung lesion of a spontaneously mummified, 1000-year-old adult female body in southern Peru. This provides the most specific evidence possible for the pre-Columbian… Expand
377 Citations
Outbreak of tuberculosis in a 2000-year-old Chinese population.
  • 24
  • PDF
Identification of Mycobacterium DNA in an Egyptian Pott's disease of 5,400 years old.
  • 108
Mycobacterium tuberculosis complex DNA in calcified pleura from remains 1400 years old
  • 99
Pre-Columbian tuberculosis in northern Chile: molecular and skeletal evidence.
  • 149
Genotypic analysis of Mycobacterium tuberculosis from medieval human remains.
  • 96
  • Highly Influenced
  • PDF
Tuberculosis: from prehistory to Robert Koch, as revealed by ancient DNA.
  • 177
  • PDF
Detection of Mycobacterial DNA in Andean Mummies
  • 83
  • Highly Influenced
  • PDF