Identification of Mre11 as a target for heat radiosensitization.


Thermal radiosensitization is believed to be mediated by an inhibition of double-strand break (DSB) repair, but the exact mechanism of radiosensitization remains to be elucidated. Previously, we demonstrated that proteins of the Mre11/Rad50/Nbs1 complex (MRN) translocate from the nucleus to the cytoplasm in cells have that been heated or heated and then… (More)


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@article{Dynlacht2011IdentificationOM, title={Identification of Mre11 as a target for heat radiosensitization.}, author={Joseph R. Dynlacht and Christopher N. Batuello and Jennifer T Lopez and Kyung Keun Kim and John J Turchi}, journal={Radiation research}, year={2011}, volume={176 3}, pages={323-32} }