Identification of Mood-Relevant Brain Connections Using a Continuous, Subject-Driven Rumination Paradigm.

@article{Milazzo2016IdentificationOM,
  title={Identification of Mood-Relevant Brain Connections Using a Continuous, Subject-Driven Rumination Paradigm.},
  author={Anna-Clare Milazzo and Bernard Ng and Heidi Jiang and William R. Shirer and G. Varoquaux and Jean Baptiste Poline and Bertrand Thirion and Michael D. Greicius},
  journal={Cerebral cortex},
  year={2016},
  volume={26 3},
  pages={933-942}
}
Rumination, an internal cognitive state characterized by recursive thinking of current self-distress and past negative events, has been found to correlate with the development of depressive disorders. Here, we investigated the feasibility of using connectivity for distinguishing different emotional states induced by a novel free-streaming, subject-driven experimental paradigm. Connectivity between 78 functional regions of interest (ROIs) within 14 large-scale networks and 6 structural ROIs… CONTINUE READING
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