Identification of MicroRNAs associated with early relapse after nephrectomy in renal cell carcinoma patients

  title={Identification of MicroRNAs associated with early relapse after nephrectomy in renal cell carcinoma patients},
  author={O. Slaby and M. R{\'e}dov{\'a} and A. Poprach and J. Nekvindov{\'a} and R. Iliev and L. Radov{\'a} and R. Lakom{\'y} and M. Svoboda and R. Vyzula},
  • O. Slaby, M. Rédová, +6 authors R. Vyzula
  • Published 2012
  • Biology, Medicine
  • Genes
  • Renal cell carcinoma (RCC) is the most common neoplasm of adult kidney. One of the important unmet medical needs in RCC is prognostic biomarker enabling identification of patients at high risk of relapse after nephrectomy. MicroRNAs (miRNAs) constitute a robust regulatory network with posttranscriptional regulatory efficiency for almost one‐half of human coding genes, including oncogenes and tumor suppressors. To identify potential prognostic miRNAs, we analyzed expression profiles in tumors of… CONTINUE READING
    93 Citations
    Expression Profiles and Clinical Significance of MicroRNAs in Papillary Renal Cell Carcinoma
    • 21
    MicroRNAs in the Pathogenesis of Renal Cell Carcinoma and Their Diagnostic and Prognostic Utility as Cancer Biomarkers
    • 19
    Clinical utility of microRNAs in renal cell carcinoma: current evidence and future perspectives
    • 7


    miRNA profiling in metastatic renal cell carcinoma reveals a tumour-suppressor effect for miR-215
    • 141
    • PDF
    MicroRNAs in Renal Cell Carcinoma: Diagnostic Implications of Serum miR-1233 Levels
    • 192
    • PDF
    MicroRNA profiling of human kidney cancer subtypes.
    • 147
    • Highly Influential
    • PDF
    Molecular Classification of Adult Renal Epithelial Neoplasms Using MicroRNA Expression and Virtual Karyotyping
    • 29
    • Highly Influential
    Accurate molecular classification of renal tumors using microRNA expression.
    • 99
    • Highly Influential
    MicroRNA profiling of clear cell renal cell cancer identifies a robust signature to define renal malignancy
    • 220
    Differential expression profiling of microRNAs and their potential involvement in renal cell carcinoma pathogenesis.
    • 204
    • Highly Influential
    • PDF
    Accurate molecular classification of kidney cancer subtypes using microRNA signature.
    • 180
    • Highly Influential
    [DNA and microRNA microarray technologies in diagnostics and prediction for patients with renal cell carcinoma].
    • 5
    • PDF
    Identification of a microRNA panel for clear-cell kidney cancer.
    • 219
    • Highly Influential
    • PDF