Identification of MicroRNAs associated with early relapse after nephrectomy in renal cell carcinoma patients

@article{Slaby2012IdentificationOM,
  title={Identification of MicroRNAs associated with early relapse after nephrectomy in renal cell carcinoma patients},
  author={O. Slaby and M. R{\'e}dov{\'a} and A. Poprach and J. Nekvindov{\'a} and R. Iliev and L. Radov{\'a} and R. Lakom{\'y} and M. Svoboda and R. Vyzula},
  journal={Genes},
  year={2012},
  volume={51}
}
  • O. Slaby, M. Rédová, +6 authors R. Vyzula
  • Published 2012
  • Biology, Medicine
  • Genes
  • Renal cell carcinoma (RCC) is the most common neoplasm of adult kidney. One of the important unmet medical needs in RCC is prognostic biomarker enabling identification of patients at high risk of relapse after nephrectomy. MicroRNAs (miRNAs) constitute a robust regulatory network with posttranscriptional regulatory efficiency for almost one‐half of human coding genes, including oncogenes and tumor suppressors. To identify potential prognostic miRNAs, we analyzed expression profiles in tumors of… CONTINUE READING
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