Identification of Marek's disease virus-specific antigens in Marek's disease lymphoblastoid cell lines using monoclonal antibody against virus-specific phosphorylated polypeptides.

@article{Ikuta1985IdentificationOM,
  title={Identification of Marek's disease virus-specific antigens in Marek's disease lymphoblastoid cell lines using monoclonal antibody against virus-specific phosphorylated polypeptides.},
  author={Kazufumi Ikuta and Kousuke Nakajima and Makoto Naito and S. Ann and Shigeharu Ueda and Satoshi Kato and Kanji Hirai},
  journal={International journal of cancer},
  year={1985},
  volume={35 2},
  pages={257-64}
}
For identification of the antigens specific to Marek's disease virus (MDV) in virus-non-producer lymphoblastoid cell lines established from a tumor of Marek's disease (MD), hybridomas producing monoclonal antibodies (MAbs) against the antigens were isolated. Immunogens for preparation of the hybridomas were purified from the lysate of an MD-lymphoblastoid cell line, MSB1, by affinity chromatography coupled with chicken anti-MDV serum immunoglobulin G. Three of the MAbs obtained, MB1, MB2 and… CONTINUE READING

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