Identification of MYO4, a second class V myosin gene in yeast.

  title={Identification of MYO4, a second class V myosin gene in yeast.},
  author={Brian K. Haarer and Annett Petzold and Sue H. Lillie and Susan S. Brown},
  journal={Journal of cell science},
  volume={107 ( Pt 4)},
We have isolated a fourth myosin gene (MYO4) in yeast (Saccharomyces cerevisiae). MYO4 encodes a approximately 170 kDa (1471 amino acid) class V myosin, using the classification devised by Cheney et al. (1993a; Cell Motil. Cytoskel. 24, 215-223); the motor domain is followed by a neck region containing six putative calmodulin-binding sites and a tail with a short potential 'coiled-coil' domain. A comparison with other myosins in GenBank reveals that Myo4 protein is most closely related to the… CONTINUE READING