Identification of Interferon-Stimulated Gene Proteins That Inhibit Human Parainfluenza Virus Type 3.

@article{Rabbani2016IdentificationOI,
  title={Identification of Interferon-Stimulated Gene Proteins That Inhibit Human Parainfluenza Virus Type 3.},
  author={M. G. Rabbani and Michael V Ribaudo and Ju-Tao Guo and S. Barik},
  journal={Journal of virology},
  year={2016},
  volume={90 24},
  pages={11145-11156}
}
A major arm of cellular innate immunity is type I interferon (IFN), represented by IFN-α and IFN-β. Type I IFN transcriptionally induces a large number of cellular genes, collectively known as IFN-stimulated gene (ISG) proteins, which act as antivirals. The IFIT (interferon-induced proteins with tetratricopeptide repeats) family proteins constitute a major subclass of ISG proteins and are characterized by multiple tetratricopeptide repeats (TPRs). In this study, we have interrogated IFIT… CONTINUE READING
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