Identification of Hub Genes and Pathways in Zika Virus Infection Using RNA-Seq Data: A Network-Based Computational Approach

@article{BrahmaRahul2018IdentificationOH,
  title={Identification of Hub Genes and Pathways in Zika Virus Infection Using RNA-Seq Data: A Network-Based Computational Approach},
  author={BrahmaRahul and GurumayumSanathoi and N. Safina Devi and MuthaiyanMathavan and GopalJeyakodi and VenkatesanAmouda},
  journal={Viral Immunology},
  year={2018},
  volume={31},
  pages={321-332}
}
Abstract Zika virus (ZIKV), a single-strand RNA flavivirus, is transmitted primarily through Aedes aegypti. The recent outbreaks in America and unexpected association between ZIKV infection and birth defects have triggered the global attention. This vouches to understand the molecular mechanisms of ZIKV infection to develop effective drug therapy. A systems-level understanding of biological process affected by ZIKV infection in fetal brain sample led us to identify the candidate genes for… CONTINUE READING

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