Identification of Host Cell Factors Associated with Astrovirus Replication in Caco-2 Cells.

@article{Murillo2015IdentificationOH,
  title={Identification of Host Cell Factors Associated with Astrovirus Replication in Caco-2 Cells.},
  author={Andrea Murillo and Rosario Vera-Estrella and Bronwyn J Barkla and Ernesto M{\'e}ndez and Carlos F Arias},
  journal={Journal of virology},
  year={2015},
  volume={89 20},
  pages={10359-70}
}
UNLABELLED Astroviruses are small, nonenveloped viruses with a single-stranded positive-sense RNA genome causing acute gastroenteritis in children and immunocompromised patients. Since positive-sense RNA viruses have frequently been found to replicate in association with membranous structures, in this work we characterized the replication of the human astrovirus serotype 8 strain Yuc8 in Caco-2 cells, using density gradient centrifugation and free-flow zonal electrophoresis (FFZE) to… CONTINUE READING