Identification of Herpes TATT-binding protein.

@article{Wyrwicz2007IdentificationOH,
  title={Identification of Herpes TATT-binding protein.},
  author={Lucjan Stanislaw Wyrwicz and Leszek Rychlewski},
  journal={Antiviral research},
  year={2007},
  volume={75 2},
  pages={167-72}
}
The regulation of viral gene expression is a compilation of virus and host factors influencing the transcription machinery. In Epstein-Barr Virus (EBV) a distinct regulatory element utilizing the TATT-box was described. The motif is present in promoters of lytic cycle genes and resembles a crucial host genome motif (TATA-box). Since the binding specificity of eukaryotic proteins recognizing TATA-box (TBP) was determined and no specific preference for interaction with TATT motif was found, we… CONTINUE READING