Identification of GABRA1 and LAMA2 as new DNA methylation markers in colorectal cancer.

@article{Lee2011IdentificationOG,
  title={Identification of GABRA1 and LAMA2 as new DNA methylation markers in colorectal cancer.},
  author={Sunwoo Lee and Taejeong Oh and Hyuncheol Chung and Sunyoung Rha and Changjin Kim and Youngho Moon and Benjamin Douglas Hoehn and Dong Jun Jeong and Seunghoon Lee and Namkyu Kim and Chanhee Park and Miae Yoo and Sungwhan An},
  journal={International journal of oncology},
  year={2011},
  volume={40 3},
  pages={
          889-98
        }
}
Aberrant methylation of CpG islands in the promoter region of genes is a common epigenetic phenomenon found in early cancers. Therefore conducting genome-scale methylation studies will enhance our understanding of the epigenetic etiology behind carcinogenesis by providing reliable biomarkers for early detection of cancer. To discover novel hypermethylated genes in colorectal cancer by genome-wide search, we first defined a subset of… CONTINUE READING

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