Identification of Escherichia coli O157:H7 genomic regions conserved in strains with a genotype associated with human infection.

@article{Steele2007IdentificationOE,
  title={Identification of Escherichia coli O157:H7 genomic regions conserved in strains with a genotype associated with human infection.},
  author={Marina Steele and Kim A Ziebell and Yongxiang Zhang and Andrew Benson and Paulina Konczy and R. V. Johnson and Victor P. J. Gannon},
  journal={Applied and environmental microbiology},
  year={2007},
  volume={73 1},
  pages={22-31}
}
Beta-glucuronidase-negative, sorbitol-nonfermenting isolates of Shiga toxin-producing Escherichia coli O157 comprise part of a clone complex of related enterohemorrhagic E. coli isolates. High-resolution genotyping shows that the O157 populations have diverged into two different lineages that appear to have different ecologies. To identify genomic regions unique to the most common human-associated genotype, suppression subtractive hybridization was used to identify DNA sequences present in two… CONTINUE READING