Identification of EphrinB1 expression in prostatic mesenchyme and a role for EphB-EphrinB signalling in prostate development.

@article{Ashley2010IdentificationOE,
  title={Identification of EphrinB1 expression in prostatic mesenchyme and a role for EphB-EphrinB signalling in prostate development.},
  author={George R. Ashley and O. Cathal Grace and Griet Vanpoucke and Axel A. Thomson},
  journal={Differentiation; research in biological diversity},
  year={2010},
  volume={80 2-3},
  pages={89-98}
}
Paracrine signalling from mesenchyme to epithelium plays a key role in regulating prostate organogenesis and it is important to identify the mesenchymally expressed molecules that regulate organ growth, though currently few such molecules are known. Tyrosine kinase signalling via EphB receptors has been characterised in many developmental processes, and EphB3 mRNA expression was detected in prostate inductive mesenchyme in previous gene profiling studies. This led us to examine the expression… CONTINUE READING