Identification of Entamoeba histolytica thiol-specific antioxidant as a GalNAc lectin-associated protein.

@article{Hughes2003IdentificationOE,
  title={Identification of Entamoeba histolytica thiol-specific antioxidant as a GalNAc lectin-associated protein.},
  author={Molly A. Hughes and Constance W. Lee and Christopher F Holm and Salil Ghosh and Andrew Mills and Lauren A. Lockhart and Sharon L Reed and Barbara J. Mann},
  journal={Molecular and biochemical parasitology},
  year={2003},
  volume={127 2},
  pages={113-20}
}
Entamoeba histolytica is a human intestinal parasite that causes amebic dysentery. A cell surface amebic adhesin, the galactose and N-acetyl-D-galactosamine inhibitable (GalNAc) lectin mediates amebic adherence to and contact-dependent killing of host cells. Previous work has suggested that the GalNAc lectin transduces signals via protein interactions with its short cytoplasmic domain. We used a yeast two-hybrid system to screen an E. histolytica cDNA library for proteins that interact with the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…