Identification of DNA variants in the SNAP-25 gene and linkage study of these polymorphisms and attention-deficit hyperactivity disorder

@article{Barr2000IdentificationOD,
  title={Identification of DNA variants in the SNAP-25 gene and linkage study of these polymorphisms and attention-deficit hyperactivity disorder},
  author={Cathy L Barr and Yu Feng and Karen G. Wigg and S Bloom and Wendy Roberts and Molly A. Malone and Russell J. Schachar and Rosemary Tannock and James L. Kennedy},
  journal={Molecular Psychiatry},
  year={2000},
  volume={5},
  pages={405-409}
}
The gene for the synaptic vesicle docking fusion protein, synaptosomal-associated protein of 25 kDa (SNAP-25), has been implicated in the etiology of attention-deficit hyperactivity disorder (ADHD) based on the mouse mutant strain coloboma. This neutron-irradiation induced mouse strain is hemizygous for the deletion of the SNAP-25 gene and displays spontaneous hyperactivity that is responsive to dextroamphetamine. Because of these characteristics, this strain has been suggested to be a mouse… Expand

Paper Mentions

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ConditionsAttention Deficit Hyperactivity Disorder
InterventionBehavioral
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TLDR
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TLDR
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Allelic variants of SNAP25 in a family-based sample of ADHD
TLDR
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