• DOI:10.1186/s12935-019-0770-9
Corpus ID: 71147573

Identification of DNA methylation-driven genes in esophageal squamous cell carcinoma: a study based on The Cancer Genome Atlas

@article{Lu2019IdentificationOD,
  title={Identification of DNA methylation-driven genes in esophageal squamous cell carcinoma: a study based on The Cancer Genome Atlas},
  author={T. Lu and D. Chen and Y. Wang and X. Sun and S. Li and Shuncheng Miao and Y. Wo and Y. Dong and Xiaoliang Leng and Wenxing Du and Wenjie Jiao},
  journal={Cancer Cell International},
  year={2019},
  volume={19}
}

T. Lu, D. Chen, +8 authors Wenjie Jiao

Published 2019

Biology, Medicine

Cancer Cell International

BackgroundAberrant DNA methylations are significantly associated with esophageal squamous cell carcinoma (ESCC). In this study, we aimed to investigate the DNA methylation-driven genes in ESCC by integrative bioinformatics analysis.MethodsData of DNA methylation and transcriptome profiling were downloaded from TCGA database. DNA methylation-driven genes were obtained by methylmix R package. David database and ConsensusPathDB were used to perform gene ontology (GO) analysis and pathway analysis… CONTINUE READING

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