Identification of Candidate Transcription Factor Binding Sites in the Cattle Genome

  title={Identification of Candidate Transcription Factor Binding Sites in the Cattle Genome},
  author={Derek M. Bickhart and George E. Liu},
  booktitle={Genomics, Proteomics & Bioinformatics},
A resource that provides candidate transcription factor binding sites (TFBSs) does not currently exist for cattle. Such data is necessary, as predicted sites may serve as excellent starting locations for future omics studies to develop transcriptional regulation hypotheses. In order to generate this resource, we employed a phylogenetic footprinting approach-using sequence conservation across cattle, human and dog-and position-specific scoring matrices to identify 379,333 putative TFBSs upstream… CONTINUE READING


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