Identification of Candida albicans genes induced during thrush offers insight into pathogenesis.

@article{Cheng2003IdentificationOC,
  title={Identification of Candida albicans genes induced during thrush offers insight into pathogenesis.},
  author={Shaoji Cheng and Cornelius J. Clancy and Mary Ann Checkley and Martin Handfield and Jeffrey D. Hillman and Ann Progulske-Fox and Alfred S Lewin and Paul L. Fidel and Minh Hong Nguyen},
  journal={Molecular microbiology},
  year={2003},
  volume={48 5},
  pages={1275-88}
}
Candida albicans causes a wide spectrum of diseases, ranging from mucocutaneous infections like oral thrush to disseminated candidiasis. Screening for C. albicans genes expressed within infected hosts might advance understanding of candidal pathogenesis, but is impractical using existing techniques. In this study, we used an antibody-based strategy to identify C. albicans genes expressed during thrush. We adsorbed sera from HIV-infected patients with thrush against candidal cells grown in vitro… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…