Identification of CD23 as a functional receptor for the proinflammatory cytokine AIMP1/p43.

@article{Kwon2012IdentificationOC,
  title={Identification of CD23 as a functional receptor for the proinflammatory cytokine AIMP1/p43.},
  author={Hyuckryul Kwon and Min Chul Park and Dae Gyu Kim and Keewon Cho and Young Woo Park and Jung Min Han and Sunghoon Kim},
  journal={Journal of cell science},
  year={2012},
  volume={125 Pt 19},
  pages={
          4620-9
        }
}
Aminoacyl-tRNA-synthetase-interacting multifunctional protein 1 (AIMP1/p43) can be secreted to trigger proinflammatory molecules while it is predominantly bound to a cytoplasmic macromolecular protein complex that contains several different aminoacyl-tRNA synthetases. Although its activities as a secreted signaling factor have been well characterized, the functional receptor for its proinflammatory activity has not yet identified. In this study, we have identified the receptor molecule for… CONTINUE READING
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