Identification of C-terminal domain residues involved in protein kinase A-mediated potentiation of kainate receptor subtype 6.

@article{Kornreich2007IdentificationOC,
  title={Identification of C-terminal domain residues involved in protein kinase A-mediated potentiation of kainate receptor subtype 6.},
  author={Bruce G. Kornreich and L Niu and Mark S Roberson and Robert E. Oswald},
  journal={Neuroscience},
  year={2007},
  volume={146 3},
  pages={1158-68}
}
Glutamate receptors are the major excitatory receptors in the vertebrate CNS and have been implicated in a number of physiological and pathological processes. Previous work has shown that glutamate receptor function may be modulated by protein kinase A (PKA)-mediated phosphorylation, although the molecular mechanism of this potentiation has remained unclear. We have investigated the phosphorylation of specific amino acid residues in the C-terminal cytoplasmic domain of the rat kainate receptor… CONTINUE READING
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