Identification of Bacterial Protein O-Oligosaccharyltransferases and Their Glycoprotein Substrates

@inproceedings{Schulz2013IdentificationOB,
  title={Identification of Bacterial Protein O-Oligosaccharyltransferases and Their Glycoprotein Substrates},
  author={Benjamin L Schulz and Freda E. C. Jen and Peter M. Power and Christopher E Jones and Kate L. Fox and Shan Chi Ku and Joanne T. Blanchfield and Michael P Jennings},
  booktitle={PloS one},
  year={2013}
}
O-glycosylation of proteins in Neisseria meningitidis is catalyzed by PglL, which belongs to a protein family including WaaL O-antigen ligases. We developed two hidden Markov models that identify 31 novel candidate PglL homologs in diverse bacterial species, and describe several conserved sequence and structural features. Most of these genes are adjacent to… CONTINUE READING