Identification of Bacillus subtilis SipW as a bifunctional signal peptidase that controls surface-adhered biofilm formation.

@article{Terra2012IdentificationOB,
  title={Identification of Bacillus subtilis SipW as a bifunctional signal peptidase that controls surface-adhered biofilm formation.},
  author={Rebecca Terra and Nicola R Stanley-Wall and Guoqiang Cao and Beth A. Lazazzera},
  journal={Journal of bacteriology},
  year={2012},
  volume={194 11},
  pages={
          2781-90
        }
}
Biofilms of microbial cells encased in an exopolymeric matrix can form on solid surfaces, but how bacteria sense a solid surface and upregulate biofilm genes is largely unknown. We investigated the role of the Bacillus subtilis signal peptidase, SipW, which has a unique role in forming biofilms on a solid surface and is not required at an air-liquid interface. Surprisingly, we found that the signal peptidase activity of SipW was not required for solid-surface biofilms. Furthermore, a SipW… CONTINUE READING
Highly Cited
This paper has 26 citations. REVIEW CITATIONS
Related Discussions
This paper has been referenced on Twitter 3 times. VIEW TWEETS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Structural changes of TasA in biofilm formation of Bacillus subtilis

Proceedings of the National Academy of Sciences of the United States of America • 2018
View 1 Excerpt

Fusarium culmorum affects expression of biofilm formation key genes in Bacillus subtilis

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] • 2016