Identification of Amino Acids that Account for Long-Range Interactions in Two Triosephosphate Isomerases from Pathogenic Trypanosomes

@inproceedings{GarcaTorres2011IdentificationOA,
  title={Identification of Amino Acids that Account for Long-Range Interactions in Two Triosephosphate Isomerases from Pathogenic Trypanosomes},
  author={Itzhel Garc{\'i}a-Torres and Nallely Cabrera and Alfredo Torres-Larios and M{\'o}nica Rodr{\'i}guez-Bola{\~n}os and Selma D{\'i}az-Mazariegos and Armando G{\'o}mez-Puyou and Ruy Perez-Montfort},
  booktitle={PloS one},
  year={2011}
}
For a better comprehension of the structure-function relationship in proteins it is necessary to identify the amino acids that are relevant for measurable protein functions. Because of the numerous contacts that amino acids establish within proteins and the cooperative nature of their interactions, it is difficult to achieve this goal. Thus, the study of protein-ligand interactions is usually focused on local environmental structural differences. Here, using a pair of triosephosphate isomerase… CONTINUE READING

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