Identification of 5 novel feline erythrocyte antigens based on the presence of naturally occurring alloantibodies.

@article{Binvel2020IdentificationO5,
  title={Identification of 5 novel feline erythrocyte antigens based on the presence of naturally occurring alloantibodies.},
  author={Marie Binvel and Julie Arsenault and Boris Depr{\'e} and Marie-Claude Blais},
  journal={Journal of veterinary internal medicine},
  year={2020}
}
BACKGROUND Since the discovery of the Mik antigen, several studies have described blood incompatibilities unrelated to the AB system in cats. OBJECTIVE To estimate the prevalence of cats with non-AB incompatibilities associated with naturally occurring alloantibodies (NOAb), and to begin mapping the corresponding feline erythrocyte antigens (FEA). ANIMALS Two hundred and fifty-eight type A cats. METHODS Prospectively, cats were evaluated for the presence of NOAb by crossmatching in groups… 
4 Citations
Characterization of post-transfusion anti-FEA 1 alloantibodies in transfusion-naive FEA 1-negative cats.
TLDR
The results confirm the potential immunogenicity of FEA 1 and support crossmatching prior to a blood transfusion, even in transfusion-naive cats and better document the clinical importance of these post-transfusion antibodies.
Feline Blood Groups: A Systematic Review of Phylogenetic and Geographical Origin
TLDR
This systematic review describes data from previously published reports about cat blood types and cat breeds and fills gaps in the literature on the AB system and, in particular, the Mik group are highlighted.
Wild Felids Blood Group System
TLDR
Insight is given into the wild felids blood groups potential for zoo transfusion medicine and phylogenetic studies in order to help support reintroduction projects and to preserve genetic diversity.

References

SHOWING 1-10 OF 43 REFERENCES
Alloantibodies against A and B blood types in cats.
The AB blood group system of cats.
  • L. Auer, K. Bell
  • Biology
    Animal blood groups and biochemical genetics
  • 1981
TLDR
The blood group system, AB, was investigated in more detail, both genetically and serologically, and preliminary genetic studies indicated that the A gene is dominant to the B in the usual situation and hypotheses to explain the occurrence of the AB phenotype are discussed.
Prevalence of naturally occurring non‐AB blood type incompatibilities in cats and influence of crossmatch on transfusion outcomes
TLDR
The prevalence of naturally occurring non‐AB alloantibodies detectable by tube crossmatch is sufficiently high to justify the recommendation to perform a crossmatch before all (including the first) RBC transfusions in cats.
Comparison of five blood-typing methods for the feline AB blood group system.
TLDR
Current laboratory and in-clinic methods provide simple and accurate typing for the feline AB blood group system with few discrepancies.
Distribution of feline AB blood types: a review of frequencies and its implications in the Iberian Peninsula
TLDR
Although the calculated potential risks of transfusion reaction in unmatched transfusions and neonatal isoerythrolysis were low, blood typing prior to blood transfusion and blood typing of cats for breeding purposes are highly recommended.
A newly recognized blood group in domestic shorthair cats: the Mik red cell antigen.
TLDR
The absence of this novel Mik red cell antigen can be associated with naturally occurring anti-Mik alloantibodies and can elicit an acute hemolytic transfusion reaction after an AB-matched blood transfusion.
Feline blood genotyping versus phenotyping, and detection of non-AB blood type incompatibilities in UK cats.
TLDR
No conclusive evidence for non-AB blood type incompatibilities was found and unknown mutation(s) associated with phenotype B, resulting in false AA or Ab genotyping, were evident in a small number of cases in this study.
Prevalence of feline blood groups in the Montreal area of Quebec, Canada.
TLDR
The frequency of type B was higher than expected, which reinforces the recommendation to ensure blood compatibility of the recipient and donor before transfusion through typing and possibly cross-matching as well.
Detection of naturally occurring alloantibody by an in‐clinic antiglobulin‐enhanced and standard crossmatch gel column test in non‐transfused domestic shorthair cats
TLDR
AB typing using immunochromatographic strip is as accurate as laboratory flow cytometry, and the 2 XM methods had good agreement with additional incompatibilities being recognized by the AGC XM beyond A‐B mismatches.
Characterization of Anti-Dal Alloantibodies Following Sensitization of Two Dal-Negative Dogs
TLDR
The results support the recommendations that previously transfused dogs be crossmatched starting 4 days posttransfusion and for the animal’s lifetime, and the polyclonal anti-Dal antibodies produced will allow blood typing of a significant number of dogs, especially transfusion dogs facing blood incompatibilities and canine blood donors.
...
1
2
3
4
5
...