Identification of N,N-bis(1-pentylindol-3-yl-carboxy)naphthylamine (BiPICANA) found in an herbal blend product in the Tokyo metropolitan area and its cannabimimetic effects evaluated by in vitro [35S]GTPγS binding assays

@article{Nakajima2014IdentificationON,
  title={Identification of N,N-bis(1-pentylindol-3-yl-carboxy)naphthylamine (BiPICANA) found in an herbal blend product in the Tokyo metropolitan area and its cannabimimetic effects evaluated by in vitro [35S]GTPγS binding assays},
  author={J. Nakajima and Misako Takahashi and Nozomi Uemura and T. Seto and H. Fukaya and J. Suzuki and M. Yoshida and Maiko Kusano and H. Nakayama and K. Zaitsu and A. Ishii and Takako Moriyasu and D. Nakae},
  journal={Forensic Toxicology},
  year={2014},
  volume={33},
  pages={84-92}
}
During our careful survey of unregulated psychotropic drugs in June 2013 in the Tokyo metropolitan area, we found a new compound in a herbal product. It was identified as an analog of NNEI (MN-24) and differed in that its molecule possessed another N-pentyl indole-carbonyl group: N, N-bis(1-pentylindol-3-yl-carboxy)naphtylamine (BiPICANA, compound 2). Compound 2 was purified by silica and octadecyl group bonded type silica gel (C18, ODS) columns and confirmed by liquid chromatography–mass… Expand
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