Identification of β-chain of Fo F1 -ATPase in apoptotic cell population induced by Microplitis bicoloratus bracovirus and its role in the development of Spodoptera litura.

@article{Kou2017IdentificationO,
  title={Identification of $\beta$-chain of Fo F1 -ATPase in apoptotic cell population induced by Microplitis bicoloratus bracovirus and its role in the development of Spodoptera litura.},
  author={Tian-chao Kou and Yuede Liu and Ming Li and Yang Yang and Wei Zhang and Ji-Hui Cui and Xue-Wen Zhang and Shu-Mei Dong and Sha Xu and Shan You and Dongshuai Yu and Zunyu Pang and Kaijun Luo},
  journal={Archives of insect biochemistry and physiology},
  year={2017},
  volume={95 2}
}
Two physiological changes of Spodoptera litura parasitized by Microplitis bicoloratus are hemocyte-apoptosis and retarded immature development. β-Chain of Fo F1 -ATPase was found from a S. litura transcriptome. It belongs to a conserved P-loop NTPase superfamily, descending from a common ancestor of Lepidopteran clade. However, the characterization of β-chain of ATPase in apoptotic cells and its involvement in development remain unknown. Here, the ectopic expression and endogenous Fo F1 -ATPase… 
4 Citations
Inhibition of translation initiation factor eIF4A is required for apoptosis mediated by Microplitis bicoloratus bracovirus.
TLDR
Findings suggested that MbBV inhibited the expression of eIF4A, which was required for apoptosis mediated by MbV, which will contribute to biological pest control and enhance the understanding of molecular mechanisms underlying polydnavirus-parasitoid-host interaction.
Spodoptera litura cyclophilin A is required for Microplitis bicoloratus bracovirus-induced apoptosis during insect cellular immune response.
TLDR
It is found that expression of cyclophilin A (CypA) was significantly upregulated in Spodoptera litura hemocytes at 6-day post-parasitization, suggesting that the upregulation of CypA is linked to MbBV infection in insect cells.
Microplitis bicoloratus bracovirus regulates cyclophilin A-apoptosis-inducing factor interaction to induce cell apoptosis in the insect immunosuppressive process.
TLDR
The results demonstrate that the CypA-AIF interaction plays an important role in MbBV-induced innate immune suppression and will help to clarify aspects of insect immunological mechanisms and will be relevant to biological pest control.

References

SHOWING 1-10 OF 30 REFERENCES
A Transcriptome Analysis Suggests Apoptosis-Related Signaling Pathways in Hemocytes of Spodoptera litura After Parasitization by Microplitis bicoloratus
TLDR
A new RNAseq-based comparative analysis of the hemocytes transcriptomes of non-parasitized and parasitized S. litura hemocytes suggests that M. bicoloratus parasitism may regulate host mitochondria to trigger internucleosomal DNA fragmentation and facilitates the identification of immunosuppression-related genes.
Disruption effect of Microplitis bicoloratus polydnavirus EGF-like protein, MbCRP, on actin cytoskeleton in lepidopteran insect hemocytes.
TLDR
Results suggest that expression of MbCRP in lepidopteran insect cells is related to the disruption of the actin cytoskeleton.
Replication of Spodoptera exigua nucleopolyhedrovirus in permissive and non-permissive lepidopteran cell lines.
TLDR
Findings indicate that the SeMNPV replication was restricted at various points in dependence upon each cell line, as well as indicating that the infected CLS-79 cells underwent apoptosis.
A Role for Innexin2 and Innexin3 Proteins from Spodoptera litura in Apoptosis
TLDR
This study showed that Sf9 and Spli221 cells undergo low level apoptosis under normal culture conditions, but not Hi5 cells, which suggests that innexon-promoted apoptosis may be involving the PI3K/Akt signaling pathway.
A bacterial ecto‐triphosphate diphosphohydrolase similar to human CD39 is essential for intracellular multiplication of Legionella pneumophila
TLDR
This is the first time a bacterial ecto‐NTPDase has been implicated in virulence and was recovered in lower numbers from macrophages, alveolar epithelial cells and the amoeba, Hartmannella vermiformis compared with wild‐type L. pneumophila.
Developmental Control of a Lepidopteran Pest Spodoptera exigua by Ingestion of Bacteria Expressing dsRNA of a Non-Midgut Gene
TLDR
The results suggest that SeCHSA dsRNA may be useful as a means of insect pest control.
A message emerging from development: the repression of mitochondrial β-F1-ATPase expression in cancer
TLDR
How the study of energy metabolism during liver development forced the encounter with Warburg’s postulates and prompted us to study the mechanisms that regulate the biogenesis of mitochondria in the cancer cell is summarized.
...
...