Identification by [99mTc]ECD SPECT of anterior cingulate hypoperfusion in progressive supranuclear palsy, in comparison with Parkinson’s disease

@article{Varrone2006IdentificationB,
  title={Identification by [99mTc]ECD SPECT of anterior cingulate hypoperfusion in progressive supranuclear palsy, in comparison with Parkinson’s disease},
  author={Andrea Varrone and Marco Pagani and Elena Salvatore and Dario Salmaso and Valeria Ada Sansone and Marianna Amboni and Flavio Nobili and Giuseppe De Michele and Alessandro Filla and Paolo Barone and Sabina Pappat{\`a} and Marco Salvatore},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2006},
  volume={34},
  pages={1071-1081}
}
Progressive supranuclear palsy (PSP) is an akinetic-rigid syndrome that can be difficult to differentiate from Parkinson’s disease (PD), particularly at an early stage. [99mTc]ethyl cysteinate dimer (ECD) SPECT could represent a widely available tool to assist in the differential diagnosis. In this study we used voxel-based analysis and Computerised Brain Atlas (CBA)-based principal component analysis (PCA) of [99mTc]ECD SPECT data to test whether: (1) specific patterns of rCBF abnormalities… CONTINUE READING

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