Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomas

@article{ster2011IdentificationAV,
  title={Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomas},
  author={B. {\O}ster and K. Thorsen and P. Lamy and T. Wojdacz and L. Hansen and K. Birkenkamp-Demtr{\"o}der and K. S{\o}rensen and S. Laurberg and T. {\O}rntoft and C. Andersen},
  journal={International Journal of Cancer},
  year={2011},
  volume={129}
}
In our study, whole‐genome methylation arrays were applied to identify novel genes with tumor specific DNA methylation of promoter CpG islands in pre‐malignant and malignant colorectal lesions. Using a combination of Illumina HumanMethylation27 beadchips, Methylation‐Sensitive High Resolution Melting (MS‐HRM) analysis, and Exon arrays (Affymetrix) the DNA methylation pattern of ∼14,000 genes and their transcript levels were investigated in six normal mucosas, six adenomas and 30 MSI and MSS… Expand
A panel of genes methylated with high frequency in colorectal cancer
A genome-wide DNA methylation study in colorectal carcinoma
Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips
Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas
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