Identification and validation of a two-gene expression index for subtype classification and prognosis in Diffuse Large B-Cell Lymphoma

@inproceedings{Xu2015IdentificationAV,
  title={Identification and validation of a two-gene expression index for subtype classification and prognosis in Diffuse Large B-Cell Lymphoma},
  author={Qinghua Xu and Cong Tan and Shujuan Ni and Qifeng Wang and Fei Wu and Fang ai Liu and Xun Ye and Xia Meng and Weiqi Sheng and Xiang Du},
  booktitle={Scientific reports},
  year={2015}
}
The division of diffuse large B-cell lymphoma (DLBCL) into germinal center B-cell-like (GCB) and activated B-cell-like (ABC) subtypes based on gene expression profiling has proved to be a landmark in understanding the pathogenesis of the disease. This study aims to identify a novel biomarker to facilitate the translation of research into clinical practice. Using a training set of 350 patients, we identified a two-gene expression signature, "LIMD1-MYBL1 Index", which is significantly associated… CONTINUE READING

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Gene-Expression Profiling and Not Immunophenotypic Algorithms Predicts Prognosis in Patients with Diffuse Large B-Cell Lymphoma Treated with Immunochemotherapy

  • G Gutierrez-Garcia
  • Blood .
  • 2011
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