Identification and structural characterization of synthetic cathinones: N-propylcathinone, 2,4-dimethylmethcathinone, 2,4-dimethylethcathinone, 2,4-dimethyl-α-pyrrolidinopropiophenone, 4-bromo-α-pyrrolidinopropiophenone, 1-(2,3-dihydro-1H-inden-5-yl)-2-(pyrrolidin-1-yl)hexan-1-one and 2,4-dimethylis

@article{Baewicz2018IdentificationAS,
  title={Identification and structural characterization of synthetic cathinones: N-propylcathinone, 2,4-dimethylmethcathinone, 2,4-dimethylethcathinone, 2,4-dimethyl-$\alpha$-pyrrolidinopropiophenone, 4-bromo-$\alpha$-pyrrolidinopropiophenone, 1-(2,3-dihydro-1H-inden-5-yl)-2-(pyrrolidin-1-yl)hexan-1-one and 2,4-dimethylis},
  author={Agata Błażewicz and Elżbieta Bednarek and Magdalena Popławska and Natalia Olech and Jerzy Sitkowski and Lech Kozerski},
  journal={Forensic Toxicology},
  year={2018},
  volume={37},
  pages={288-307}
}
PurposeSeven synthetic cathinone derivatives detected in samples seized in Poland from clandestine laboratories: N-propylcathinone, 2,4-dimethylmethcathinone (2,4-DMMC), 2,4-dimethylethcathinone (2,4-DMEC), 2,4-dimethyl-α-pyrrolidinopropiophenone (2,4-DMPPP) and 2,4-dimethylisocathinone (4-iso-DMC), collected from smartshops: 4-bromo-α-pyrrolidinopropiophenone (4-Br-PPP) or received from an attorney 1-(2,3-dihydro-1H-inden-5-yl)-2-(pyrrolidin-1-yl)hexan-1-one (5-BPDi) were identified and… 
4 Citations
Dehydration-fragmentation mechanism of cathinones and their metabolites in ESI-CID.
TLDR
Findings presented herein indicate that the dehydrated ions in ESI-CID can be used for the structural identification of CATs, and provided evidence that CATs with tertiary amine structures do not undergo dehydration.
Metabolism of synthetic cathinones through the zebrafish water tank model: a promising tool for forensic toxicology laboratories
TLDR
ZWT model indicated to be very useful to study the metabolism of the synthetic cathinones, such as N -ethylpentylone, ethyl one, α-PVP and 4-CDC, and seems to be a potent CYP450 inhibitor in zebrafish.
The Separation and Identification of Synthetic Cathinones by Portable Low Microflow Liquid Chromatography with Dual Capillary Columns in Series and Dual Wavelength Ultraviolet Detection.
TLDR
This study ascertained the viability of a portable liquid chromatograph, operating at low μL/min flow, for the analysis of seized drugs at remote sites as well as in laboratory settings, and found this cost effective and green instrumentation has the potential to satisfy minimum international guidelines.

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To help elucidate the correct structures of new aryl α-primary amino ketone drugs by LC/MS/MS, it is essential to include odd-electron product ions in the data interpretation rules.
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