Identification and selection of cardiomyocytes during human embryonic stem cell differentiation.

  title={Identification and selection of cardiomyocytes during human embryonic stem cell differentiation.},
  author={Irit Huber and Ilanit Itzhaki and Oren Caspi and Gil Arbel and Maty Tzukerman and Amira Gepstein and Manhal Habib and Lior Yankelson and Izhak Kehat and Lior Gepstein},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  volume={21 10},
Human embryonic stem cells (hESC) are pluripotent lines that can differentiate in vitro into cell derivatives of all three germ layers, including cardiomyocytes. Successful application of these unique cells in the areas of cardiovascular research and regenerative medicine has been hampered by difficulties in identifying and selecting specific cardiac progenitor cells from the mixed population of differentiating cells. We report the generation of stable transgenic hESC lines, using lentiviral… CONTINUE READING


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