Identification and responsiveness of prolactin-containing secretory granules in clonal rat mammotrophs.

Abstract

Clonal pituitary cells (2B8) derived from embryonic Rathke's pouch epithelium of Wistar-Imamichi rats established by Ishikawa et al. (1977) were used in this study. Late-passage 2B8 cells were found to contain small secretory granules which contained immunoreactive prolactin as demonstrated by electron microscopic immunocytochemistry. When 2B8 cells were… (More)

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