Identification and regulation of a molecular module for bleb-based cell motility.

  title={Identification and regulation of a molecular module for bleb-based cell motility.},
  author={Mehdi Moazzami Goudarzi and Torsten U Banisch and Mehrpouya Balaghy Mobin and Nicola Maghelli and Katsiaryna Tarbashevich and Ina Strate and Jana van den Berg and Heiko Blaser and Sabine Bandemer and Ewa K Paluch and Jeroen Bakkers and Iva Marija Tolic-N\orrelykke and Erez Raz},
  journal={Developmental cell},
  volume={23 1},
Single-cell migration is a key process in development, homeostasis, and disease. Nevertheless, the control over basic cellular mechanisms directing cells into motile behavior in vivo is largely unknown. Here, we report on the identification of a minimal set of parameters the regulation of which confers proper morphology and cell motility. Zebrafish primordial germ cells rendered immotile by knockdown of Dead end, a negative regulator of miRNA function, were used as a platform for identifying… CONTINUE READING
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Identification and Regulation of a Molecular Module for Bleb-Based Cell Motility

  • Goudarzi
  • Developmental Cell (2012),
  • 2012
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