Identification and quantitation of unique fatty acid oxidation products in human atherosclerotic plaque using high-performance liquid chromatography.

@article{Waddington2001IdentificationAQ,
  title={Identification and quantitation of unique fatty acid oxidation products in human atherosclerotic plaque using high-performance liquid chromatography.},
  author={Emma I Waddington and Kishore Sienuarine and Ian B. Puddey and Kevin D Croft},
  journal={Analytical biochemistry},
  year={2001},
  volume={292 2},
  pages={234-44}
}
Oxidation of lipoproteins, particularly low-density lipoprotein, is thought to play a major role in the development of atherosclerosis. We set out to identify and quantitate the major fatty acid oxidation products in human atherosclerotic plaque obtained from individuals undergoing carotid endarterectomy. Oxidized lipids were extracted from plaque… CONTINUE READING