Identification and quantification of dolichol and dolichoic acid in neuromelanin from substantia nigra of the human brains⃞ Published, JLR Papers in Press, April 19, 2007.

@article{Ward2007IdentificationAQ,
  title={Identification and quantification of dolichol and dolichoic acid in neuromelanin from substantia nigra of the human brains⃞ Published, JLR Papers in Press, April 19, 2007.},
  author={W. Ward and Z. Guan and F. Zucca and R. Fariello and Reza Kordestani and L. Zecca and C. Raetz and J. Simon},
  journal={Journal of Lipid Research},
  year={2007},
  volume={48},
  pages={1457 - 1462}
}
Neuromelanin (NM) isolated from the substantia nigra of the human brain is found to contain a series of dolichoic acids (dol-CA) containing 14–20 isoprene units. This is the first observation of dol-CA in a natural system. Using internally spiked nor-dolichol and nor-dolichoic acid standards, the concentrations of dolichol (dol) and dol-CA present in NM were determined. Remarkably, dol was only four times as abundant as dol-CA in NM. The distribution of dol-CA chains lengths in NM also differed… Expand
Dolichol biosynthesis: the occurrence of epoxy dolichol in skipjack tuna liver.
The comparative biology of neuromelanin and lipofuscin in the human brain
From glycosylation disorders to dolichol biosynthesis defects: a new class of metabolic diseases
Neuromelanin of the Human Substantia Nigra: An Update
Neuromelanin organelles are specialized autolysosomes that accumulate undegraded proteins and lipids in aging human brain and are likely involved in Parkinson’s disease
Catecholaminergic neurons of mammalian brain and neuromelanin
...
1
2
3
...

References

SHOWING 1-10 OF 29 REFERENCES
Metabolism of dolichol, dolichoic acid and nordolichoic acid in cultured cells.
Distribution of Dolichol and Dolichyl Phosphate in Human Brain
Dolichol is the major lipid component of human substantia nigra neuromelanin
Characterization of the in vitro conversion of dolichol to dolichoate in bovine thyroid.
Accumulation of dolichols in brains of elderly.
Nonmembrane associated dolichol in rat liver
“Subcellular Proteomics” of Neuromelanin Granules Isolated from the Human Brain*
...
1
2
3
...