Identification and quantification of cannabinoids in Cannabis sativa L. plants by high performance liquid chromatography-mass spectrometry

@article{AizpuruaOlaizola2014IdentificationAQ,
  title={Identification and quantification of cannabinoids in Cannabis sativa L. plants by high performance liquid chromatography-mass spectrometry},
  author={Oier Aizpurua‐Olaizola and Jone Omar and Patricia Navarro and Maitane Olivares and Nestor Etxebarria and A. Usobiaga},
  journal={Analytical and Bioanalytical Chemistry},
  year={2014},
  volume={406},
  pages={7549-7560}
}
AbstractHigh performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) has been successfully applied to cannabis plant extracts in order to identify cannabinoid compounds after their quantitative isolation by means of supercritical fluid extraction (SFE). MS conditions were optimized by means of a central composite design (CCD) approach, and the analysis method was fully validated. Six major cannabinoids [tetrahydrocannabinolic acid (THCA), tetrahydrocannabinol (THC), cannabidiol… Expand
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