Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry

@article{Zhang2003IdentificationAQ,
  title={Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry},
  author={H. Zhang and X. Li and D. Martin and R. Aebersold},
  journal={Nature Biotechnology},
  year={2003},
  volume={21},
  pages={660-666}
}
  • H. Zhang, X. Li, +1 author R. Aebersold
  • Published 2003
  • Chemistry, Medicine
  • Nature Biotechnology
  • Quantitative proteome profiling using stable isotope protein tagging and automated tandem mass spectrometry (MS/MS) is an emerging technology with great potential for the functional analysis of biological systems and for the detection of clinical diagnostic or prognostic marker proteins. Owing to the enormous complexity of proteomes, their comprehensive analysis is an as-yet-unresolved technical challenge. However, biologically or clinically important information can be obtained if specific… CONTINUE READING
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