Identification and purification of an intrinsic human muscle myogenic factor that enhances muscle repair and regeneration.

Abstract

The limited ability of damaged muscle to regenerate after gross injuries is a major clinical problem. To date, there is no effective therapeutic treatment for muscle injuries. In the present study, we have examined the ability of crude and fractionated human skeletal muscle extracts to promote myogenic cell proliferation and differentiation. It was found… (More)

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