Identification and propagation of haploid human pluripotent stem cells

Abstract

Haploid human pluripotent stem cells (PSCs) integrate haploidy and pluripotency, providing a novel system for functional genomics and developmental research in humans. We have recently derived haploid human embryonic stem cells (ESCs) by parthenogenesis and demonstrated their wide differentiation potential and applicability for genetic screening. Because… (More)
DOI: 10.1038/nprot.2016.145

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