Identification and profiling of sex-biased microRNAs from sea urchin Strongylocentrotus nudus gonad by Solexa deep sequencing.

@article{Mi2014IdentificationAP,
  title={Identification and profiling of sex-biased microRNAs from sea urchin Strongylocentrotus nudus gonad by Solexa deep sequencing.},
  author={Xiao Mi and Zhenlin Wei and Zun-chun Zhou and Xianyong Lan},
  journal={Comparative biochemistry and physiology. Part D, Genomics & proteomics},
  year={2014},
  volume={10},
  pages={1-8}
}
MicroRNAs (miRNAs) are a class of endogenous small non-coding RNAs that regulate gene expression by post-transcriptional repression of messenger RNA. The echinoderm, Strongylocentrotus nudus, is an excellent model organism for studying development and commercially important as a food source. However, to date no miRNAs have been reported to modulate sex gonad differentiation in S. nudus. In this study, we constructed two small RNA libraries from male and female S. nudus gonad respectively for… CONTINUE READING

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