Identification and pharmacological characterization of succinate receptor agonists.

Abstract

BACKGROUND AND PURPOSE The succinate receptor (formerly GPR91 or SUCNR1) is described as a metabolic sensor that may be involved in homeostasis. Notwithstanding its implication in important (patho)physiological processes, the function of succinate receptors has remained ill-defined because no pharmacological tools were available. We report on the discovery… (More)
DOI: 10.1111/bph.13738

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