Identification and partial purification of human T lymphocyte colony-enhancing factor (LCEF), distinct from T cell-growth factor.


Colony growth of T lymphocytes in a soft agar culture system, following stimulation with phytohaemagglutinin (PHA), is enhanced by T cell-derived conditioned medium (CM). The putative enhancing factor present in this CM has been termed lymphocyte colony-enhancing factor (LCEF). The purification of LCEF from CM has been complicated by the fact that active CM… (More)


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