Identification and measurement of illicit drugs and their metabolites in urban wastewater by liquid chromatography-tandem mass spectrometry.

@article{Castiglioni2006IdentificationAM,
  title={Identification and measurement of illicit drugs and their metabolites in urban wastewater by liquid chromatography-tandem mass spectrometry.},
  author={S. Castiglioni and E. Zuccato and E. Crisci and C. Chiabrando and R. Fanelli and R. Bagnati},
  journal={Analytical chemistry},
  year={2006},
  volume={78 24},
  pages={
          8421-9
        }
}
Residues of illicit drugs and their metabolites that are excreted by humans may flow into and through wastewater treatment plants. The aim of this study was to develop a method for the determination of cocaine, amphetamines, morphine, cannabinoids, methadone, and some of their metabolites in wastewater. Composite 24-h samples from urban treatment plants were enriched with deuterated internal standards before solid-phase extraction. High-pressure liquid chromatography tandem mass spectrometry… Expand
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