Identification and localisation of nebulin as a thin filament component of invertebrate chordate muscles

@article{Fock1999IdentificationAL,
  title={Identification and localisation of nebulin as a thin filament component of invertebrate chordate muscles},
  author={Ulrike Fock and Horst Hinssen},
  journal={Journal of Comparative Physiology B},
  year={1999},
  volume={169},
  pages={555-560}
}
The giant actin-binding protein nebulin is regarded as a component of the thin filaments in vertebrate skeletal muscles, whereas the existence of nebulin in invertebrate muscles has not yet been demonstrated. Using the cross-reactivities of polyclonal antibodies raised against nebulin from muscles of trout and lamprey, we were able to identify nebulin in the myofibrils of the cephalochordate Branchiostoma lanceolatum (lancelet) by immunoblot and immunofluorescence techniques. The ∼720-kDa… CONTINUE READING

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Puri®cation of titin and nebulin

  • K Wang
  • Methods Enzymol
  • 1982
Highly Influential
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