Identification and importance of brown adipose tissue in adult humans.

@article{Cypess2009IdentificationAI,
  title={Identification and importance of brown adipose tissue in adult humans.},
  author={Aaron M. Cypess and Sanaz Lehman and Gethin Williams and Ilan Tal and Dean Rodman and Allison B Goldfine and F C Kuo and Edwin L. Palmer and Yu-Hua Tseng and Alessandro Doria and G. M. Kolodny and C. Ronald Kahn},
  journal={The New England journal of medicine},
  year={2009},
  volume={360 15},
  pages={
          1509-17
        }
}
BACKGROUND Obesity results from an imbalance between energy intake and expenditure. In rodents and newborn humans, brown adipose tissue helps regulate energy expenditure by thermogenesis mediated by the expression of uncoupling protein 1 (UCP1), but brown adipose tissue has been considered to have no physiologic relevance in adult humans. METHODS We analyzed 3640 consecutive (18)F-fluorodeoxyglucose ((18)F-FDG) positron-emission tomographic and computed tomographic (PET-CT) scans performed… Expand

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TLDR
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