Identification and genetic characterization of a novel circular single-stranded DNA virus in a human upper respiratory tract sample

@article{Cui2017IdentificationAG,
  title={Identification and genetic characterization of a novel circular single-stranded DNA virus in a human upper respiratory tract sample},
  author={L. Cui and B. Wu and Xiaojuan Zhu and Xiling Guo and Y. Ge and Kangchen Zhao and X. Qi and Zhiyang Shi and F. Zhu and L. Sun and Minghao Zhou},
  journal={Archives of Virology},
  year={2017},
  volume={162},
  pages={3305-3312}
}
  • L. Cui, B. Wu, +8 authors Minghao Zhou
  • Published 2017
  • Medicine, Biology
  • Archives of Virology
  • Metagenomic analysis through high-throughput sequencing is a tool for detecting both known and novel viruses. Using this technique, a novel circular single-stranded DNA (ssDNA) virus genome was discovered in respiratory secretions from a febrile traveler. The virus, named human respiratory-associated PSCV-5-like virus (HRAPLV), has a genome comprising 3,018 bases, with two major putative ORFs inversely encoding capsid (Cap) and replicase (Rep) protein and separated by two intergenic regions… CONTINUE READING
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