Identification and functional characterization of a novel human misshapen/Nck interacting kinase-related kinase, hMINK beta.

@article{Hu2004IdentificationAF,
  title={Identification and functional characterization of a novel human misshapen/Nck interacting kinase-related kinase, hMINK beta.},
  author={Yuanming Hu and Cindy Leo and Simon Yu and Betty C.B. Huang and Hank S. Wang and Mary M Shen and Ying Luo and Sarkiz Daniel-Issakani and Donald G. Payan and Xiang Xu},
  journal={The Journal of biological chemistry},
  year={2004},
  volume={279 52},
  pages={54387-97}
}
Misshapen/NIKs-related kinase (MINK) is a member of the germinal center family of kinases that are homologous to the yeast sterile 20 (Ste20) kinases and regulate a wide variety of cellular processes, including cell morphology, cytoskeletal rearrangement, and survival. Here, we present the cloning and functional characterization of a novel human Misshapen/NIKs-related kinase beta (hMINK beta) that encodes a polypeptide of 1312 amino acids. hMINK beta is ubiquitously expressed in most tissues… CONTINUE READING
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