Identification and functional analysis of the gene for type I myosin in fission yeast.

@article{Toya2001IdentificationAF,
  title={Identification and functional analysis of the gene for type I myosin in fission yeast.},
  author={Maki Toya and Fumio Motegi and Kentaro Nakano and Issei Mabuchi and Masayuki Yamamoto},
  journal={Genes to cells : devoted to molecular & cellular mechanisms},
  year={2001},
  volume={6 3},
  pages={
          187-99
        }
}
BACKGROUND Type I myosin is highly conserved among eukaryotes, and apparently plays important roles in a number of cellular processes. In the budding yeast, two myosin I species have been identified and their role in F-actin assembly has been inferred. RESULTS We cloned the fission yeast myo1 gene, which apparently encoded a myosin I protein. Disruption of myo1 was not lethal, but it caused growth retardation at high and low temperatures, sensitivity to a high concentration of KCl, and… CONTINUE READING
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