Identification and expression of the Actinobacillus actinomycetemcomitans leukotoxin gene.

Abstract

The leukotoxin produced by the oral bacterium Actinobacillus actinomycetemcomitans has been implicated in the pathogenesis of juvenile periodontitis. In order to elucidate the structure of the leukotoxin, molecular cloning of the leukotoxin gene was carried out. A DNA library of A. actinomycetemcomitans, strain JP2, was constructed by partial digestion of… (More)

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@article{Lally1989IdentificationAE, title={Identification and expression of the Actinobacillus actinomycetemcomitans leukotoxin gene.}, author={Edward T. Lally and Irene R Kieba and Donald R. Demuth and Joan C. Rosenbloom and Ellis E. Golub and Norton S. Taichman and Carolyn Winters Gibson}, journal={Biochemical and biophysical research communications}, year={1989}, volume={159 1}, pages={256-62} }