Identification and expression analysis of lymphotoxin-beta like homologues in rainbow trout Oncorhynchus mykiss.

@article{Kono2006IdentificationAE,
  title={Identification and expression analysis of lymphotoxin-beta like homologues in rainbow trout Oncorhynchus mykiss.},
  author={Tomoya Kono and Jun Zou and Steve Bird and Ram Savan and Masahiro Sakurai Toshiaki Sakai and Christopher J Secombes},
  journal={Molecular immunology},
  year={2006},
  volume={43 9},
  pages={1390-401}
}
A lymphotoxin-beta (LT-beta) gene has been cloned and sequenced in rainbow trout and provides the first conclusive evidence for the existence of LT-beta in teleost. Two isoforms of LT-beta were isolated. LT-beta1 cDNA was composed of 952 bp (with a 139 bp 5'-UTR and a 201 bp 3'-UTR) and LT-beta2 cDNA was 836 bp (with a 237 bp 5'-UTR and a 197 bp 3'-UTR) both of which translated into a protein of 203 amino acid residues. Both isoforms contained a predicted transmembrane domain of 21 amino acid… CONTINUE READING

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